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Comment
. 2021 Apr 1;49(4):e482-e483.
doi: 10.1097/CCM.0000000000004838.

Antithrombin Supplementation May Not Decrease Heparin Requirements nor Diminish the Prevalence of Bleeding and/or Thrombosis in Adult Patients on Venovenous Extracorporeal Membrane Oxygenation: Enough Evidence for a Definitive Banning Order?

Patrick M Honore  1 , Sebastien Redant, Luc Kugener, Leonel Barreto Gutierrez, Rachid Attou, Andrea Gallerani, David De Bels
Affiliations
Comment

Antithrombin Supplementation May Not Decrease Heparin Requirements nor Diminish the Prevalence of Bleeding and/or Thrombosis in Adult Patients on Venovenous Extracorporeal Membrane Oxygenation: Enough Evidence for a Definitive Banning Order?

Patrick M Honore et al. Crit Care Med. .
No abstract available

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Conflict of interest statement

The authors have disclosed that they do not have any potential conflicts of interest.

Comment on

References

    1. Panigada M, Cucino A, Spinelli E, et al. A Randomized Controlled Trial of Antithrombin Supplementation During Extracorporeal Membrane Oxygenation. Crit Care Med. 2020; 48:1636–1644
    1. du Cheyron D, Bouchet B, Bruel C, et al. Antithrombin supplementation for anticoagulation during continuous hemofiltration in critically ill patients with septic shock: A case-control study. Crit Care. 2006; 10:R45
    1. Ryerson L, Lequier L. Anticoagulation in pediatric extracorporeal life support—time for a more direct approach? Pediatr Crit Care Med. 2020; 21–9:841–843
    1. Lafargue M, Joannes-Boyau O, Honoré PM, et al. Acquired deficit of antithrombin and role of supplementation in septic patients during continuous veno-venous hemofiltration. ASAIO J. 2008; 54:124–128

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