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Review
. 2021 Mar 11:13:2329-2339.
doi: 10.2147/CMAR.S290592. eCollection 2021.

Approaches to the Diagnosis and Management of Ovarian Cancer in Pregnancy

Kaja Michalczyk  1 , Aneta Cymbaluk-Płoska  1
Affiliations
Review

Approaches to the Diagnosis and Management of Ovarian Cancer in Pregnancy

Kaja Michalczyk et al. Cancer Manag Res. .

Abstract

Ovarian cancer is one of the most common gynecological cancers diagnosed in pregnancy. Its management is often very problematic due to the proximity of the adnexa to the developing fetus and chemotherapy-related toxicity risk. Tumor markers and imagining studies play important roles in diagnosis, help differentiate benign masses from malignancy and allow to plan the treatment. Due to the physiological changes that occur in pregnancy, levels of tumor markers can be altered and reduce their diagnostic value. We review current recommendations for the management and treatment of ovarian cancer in pregnant patients considering gestational age at diagnosis, tumor histology, stage of the disease, risk of obstetrical complications, and patient's preferences.

Keywords: chemotherapy; ovarian malignancy; pregnancy; tumor markers.

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Conflict of interest statement

The authors report no conflicts of interest for this work.

Figures

Figure 1
Figure 1
Venn diagram illustrating the management of patients diagnosed with ovarian cancer in pregnancy.
See this image and copyright information in PMC

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