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Case Reports
. 2021 Feb 12;13(2):e13308.
doi: 10.7759/cureus.13308.

McKittrick-Wheelock Syndrome: A Rare Cause of Chronic Diarrhea

Abhilasha Jyala  1 , Shehriyar Mehershahi  2 , Niel Shah  3 , Danial H Shaikh  2 , Harish Patel  3
Affiliations
Case Reports

McKittrick-Wheelock Syndrome: A Rare Cause of Chronic Diarrhea

Abhilasha Jyala et al. Cureus. .

Abstract

Diarrhea is the principal cause of the majority of healthcare utilization. When diarrhea lasts longer than four weeks, it is considered chronic diarrhea. There are several causes of chronic diarrhea, but here we focus on one of the rare causes, known as McKittrick-Wheelock syndrome (MWS). We here present the case of a patient in his seventies with chronic diarrhea, found to have tubulovillous adenoma and diagnosed with McKittrick-Wheelock syndrome. We also discuss the clinical presentation, pathophysiology, and management of MWS.

Keywords: chronic diarrhea; mckittrick-wheelock syndrome; tubulovillous adenoma.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Colonoscopy: recto-sigmoid mass
Figure 2
Figure 2. Histology: tubulovillous adenoma
See this image and copyright information in PMC

References

    1. Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology. Arasaradnam RP, Brown S, Forbes A, et al. Gut. 2018;67:1380–1399. - PMC - PubMed
    1. Gastro 2013 APDW/WCOG Shanghai working party report: chronic diarrhea: definition, classification, diagnosis. Schiller LR, Pardi DS, Spiller R, et al. https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.12392. J Gastroenterol Hepatol. 2014;29:6–25. - PubMed
    1. Carcinoma of the colon. McKittrick LS, Wheelock FC. Dis Colon Rectum. 1997;40:1494–1496. - PubMed
    1. A case of giant rectal villous tumor with severe fluid-electrolyte imbalance treated by laparoscopic low anterior resection. Choi WH, Ryuk J, Kim HJ, et al. J Korean Surg Soc. 2012;82:325–329. - PMC - PubMed
    1. Adenocarcinoma of the colon associated with severe hypokalemia: report of a case. McCabe RE, Kane KK, Zintel HA, Pierson RN. Ann Surg. 1970;172:970–974. - PMC - PubMed

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