Effect of Intravitreal Injections on Retinal Imaging Metrics in Glaucomatous and Non-Glaucomatous Eyes
- PMID: 33738146
- PMCID: PMC7962983
- DOI: 10.1007/s40135-020-00235-z
Effect of Intravitreal Injections on Retinal Imaging Metrics in Glaucomatous and Non-Glaucomatous Eyes
Abstract
Purpose of review: To summarize the available literature on retinal imaging metrics in the context of intravitreal injections in glaucomatous and non-glaucomatous eyes.
Recent findings: The retinal nerve fiber layer (RNFL) in injected non-glaucomatous eyes appears to thin at a similar rate to uninjected fellow eyes. A total of four studies evaluating RNFL thinning in injected glaucomatous eyes yielded mixed results, with more recent longitudinal investigations suggesting a potential association. The ganglion cell-inner plexiform layer is also being studied as a potential endpoint in both glaucomatous and non-glaucomatous eyes following intravitreal injections.
Keywords: Ganglion cell layer; Ganglion cell-inner plexiform layer; Glaucoma; Intravitreal injections; Ocular hypertension; Optic nerve; Retinal nerve fiber layer.
Conflict of interest statement
Compliance with Ethical Standards Conflicts of Interest The authors declare that they have no conflict of interest.
References
-
- Grzybowski A, Told R, Sacu S, Bandello F, Moisseiev E, Loewenstein A et al. 2018 Update on Intravitreal Injections: Euretina Expert Consensus Recommendations. Ophthalmologica Journal international d’ophtalmologie International journal of ophthalmology Zeitschrift fur Augenheilkunde. 2018;239(4):181–93. doi: 10.1159/000486145. - DOI - PubMed
-
- Hoguet A, Chen PP, Junk AK, Mruthyunjaya P, Nouri-Mahdavi K, Radhakrishnan S et al. The Effect of Anti-Vascular Endothelial Growth Factor Agents on Intraocular Pressure and Glaucoma: A Report by the American Academy of Ophthalmology. Ophthalmology. 2019;126(4):611–22. doi: 10.1016/j.ophtha.2018.11.019. - DOI - PubMed
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