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1 Division of Reproductive Medicine, Madigan Army Medical Center, Tacoma, WA, USA. bruce.d.pier3.mil@mail.mil.
2 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, WA, 98431, USA. bruce.d.pier3.mil@mail.mil.
3 Division of Reproductive Medicine, Madigan Army Medical Center, Tacoma, WA, USA.
4 Division of Reproductive Endocrinology and Infertility, University of California, San Diego, CA, USA.
5 Reproductive Partners San Diego, San Diego, CA, USA.
6 Center for Reproductive Medicine, West Virginia University, Morgantown, WV, USA.
1 Division of Reproductive Medicine, Madigan Army Medical Center, Tacoma, WA, USA. bruce.d.pier3.mil@mail.mil.
2 Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, WA, 98431, USA. bruce.d.pier3.mil@mail.mil.
3 Division of Reproductive Medicine, Madigan Army Medical Center, Tacoma, WA, USA.
4 Division of Reproductive Endocrinology and Infertility, University of California, San Diego, CA, USA.
5 Reproductive Partners San Diego, San Diego, CA, USA.
6 Center for Reproductive Medicine, West Virginia University, Morgantown, WV, USA.
The increasing use of frozen-thawed embryo transfer (FET) cycles has magnified the focus on endometrial preparation protocols in assisted reproduction. Emerging evidence suggests that natural cycle (NC) FETs are associated with improved outcomes, and that providers should consider increasing the utilization of NC FET at the expense of the currently favored artificial cycle (AC) FET as primary method for endometrial preparation.
Celada P, Bosch E. Freeze-all, for whom, when, and how. Ups J Med Sci. 2020;125(2):104–111. doi: 10.1080/03009734.2020.1746870.
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Chen ZJ, Legro RS. Fresh versus frozen embryos in polycystic ovary syndrome. N Engl J Med. 2016;375(20):e42. doi: 10.1056/NEJMc1611871.
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Healy MW, Patounakis G, Connell MT, Devine K, DeCherney AH, Levy MJ, Hill MJ. Does a frozen embryo transfer ameliorate the effect of elevated progesterone seen in fresh transfer cycles? Fertil Steril. 2016;105(1):93–99. doi: 10.1016/j.fertnstert.2015.09.015.
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Quaas AM, Hansen KR. Time to “cool off”? Examining indications for “elective deferred frozen embryo transfer”. J Assist Reprod Genet. 2016;33(12):1551–1552. doi: 10.1007/s10815-016-0815-0.
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Maheshwari A, Pandey S, Amalraj Raja E, Shetty A, Hamilton M, Bhattacharya S. Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer? Hum Reprod Update. 2018;24(1):35–58. doi: 10.1093/humupd/dmx031.
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