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Review
. 2021 Jun;31(3):365-368.
doi: 10.1007/s10286-021-00798-2. Epub 2021 Mar 19.

Long-COVID postural tachycardia syndrome: an American Autonomic Society statement

Satish R Raj  1   2 , Amy C Arnold  3   4 , Alexandru Barboi  5 , Victoria E Claydon  6 , Jacqueline K Limberg  7 , Vera-Ellen M Lucci  6 , Mohammed Numan  8 , Amanda Peltier  9 , Howard Snapper  10 , Steven Vernino  11 ; American Autonomic Society
Affiliations
Review

Long-COVID postural tachycardia syndrome: an American Autonomic Society statement

Satish R Raj et al. Clin Auton Res. 2021 Jun.

Abstract

COVID-19 is a global pandemic that has had a devastating effect on the health and economy of much of human civilization. While the acute impacts of COVID-19 were the initial focus of concern, it is becoming clear that in the wake of COVID-19, many patients are developing chronic symptoms that have been called Long-COVID. Some of the symptoms and signs include those of postural tachycardia syndrome (POTS). Understanding and managing long-COVID POTS will require a significant infusion of health care resources and a significant additional research investment. In this document from the American Autonomic Society, we outline the scope of the problem, and the resources and research needed to properly address the impact of Long-COVID POTS.

Keywords: COVID; Long COVID; Position statement; Postural tachycardia syndrome.

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Conflict of interest statement

SRR has grant support from the Canadian Institutes of Health Research (Ottawa, Canada) and Dysautonomia International (East Moriches, NY, USA). SRR is a consultant for Lundbeck LLC and Theravance Biopharma, and serves as DSMB chair for a phase 2 study run by Arena Pharmaceuticals. SRR has received compensation for editorial activities (Associate Editor) with Autonomic Neuroscience—Basic and Clinical. ACA: Consultant for National Vaccine Injury Compensation Program, U.S. Department of Health and Human Services; research grant from Dysautonomia International. AB: None. VEC: Research grants from the Heart and Stroke Foundation of Canada, Craig H Nielsen Foundation, and International Collaboration on Repair Discoveries. JKL: None. MN: None. VEML: None. AP: None. HS: None. SV: SV has received research support from Biohaven, Dysautonomia International, Genentech, Grifols, Rex Griswold Foundation, and Athena/Quest Diagnostics (through a licensing contract) and personal compensation for consulting for Catalyst, Sage and Alterity.

References

    1. Centers for Disease Control and Prevention (2021) COVID-19 Cases, Data and Surveillance. https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/. Accessed 16 Feb 2021
    1. World Health Organization (2021) Coronavirus disease (COVID-19) weekly epidemiological update and weekly operational update. https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situatio.... Accessed 16 Feb 2021
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    1. National Institute for Health and Care Excellence (NICE) (2021) COVID-19 rapid guideline: managing the long-term effects of COVID-19. https://www.nice.org.uk/guidance/ng188. Accessed 16 Feb 2021 - PubMed
    1. Mayo Clinic (2021) COVID-19 (coronavirus): long-term effects. https://www.mayoclinic.org/coronavirus-long-term-effects/art-20490351. Accessed 20 Feb 2021

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