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Comment
. 2021 Mar 18;81(6):1126-1127.
doi: 10.1016/j.molcel.2021.02.027.

TopBP1 comes into focus

William G Dunphy  1
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TopBP1 comes into focus

William G Dunphy. Mol Cell. .
Free article

Abstract

Frattini et al. (2021) demonstrate that TopBP1 forms phase-separated nuclear condensates to promote activation of ATR in cells experiencing genomic stress.

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