Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 May;35(1):67-82.
doi: 10.1016/j.bpa.2020.11.003. Epub 2020 Nov 16.

Optimizing airway management and ventilation during prehospital advanced life support in out-of-hospital cardiac arrest: A narrative review

Affiliations
Free article
Review

Optimizing airway management and ventilation during prehospital advanced life support in out-of-hospital cardiac arrest: A narrative review

Hans van Schuppen et al. Best Pract Res Clin Anaesthesiol. 2021 May.
Free article

Abstract

Airway management and ventilation are essential components of cardiopulmonary resuscitation to achieve oxygen delivery in order to prevent hypoxic injury and increase the chance of survival. Weighing the relative benefits and downsides, the best approach is a staged strategy; start with a focus on high-quality chest compressions and defibrillation, then optimize mask ventilation while preparing for advanced airway management with a supraglottic airway device. Endotracheal intubation can still be indicated, but has the largest downsides of all advanced airway techniques. Whichever stage of airway management, ventilation and chest compression quality should be closely monitored. Capnography has many advantages and should be used routinely. Optimizing ventilation strategies, harmonizing ventilation with mechanical chest compression devices, and implementation in complex and stressful environments are challenges we need to face through collaborative innovation, research, and implementation.

Keywords: airway management; capnography; cardiopulmonary resuscitation; out-of-hospital cardiac arrest; prehospital advanced life support; ventilation.

PubMed Disclaimer

Conflict of interest statement

Declaration of competing interest Hans van Schuppen reports a research grant from the Zoll Foundation, outside the submitted work. Rudolph Koster reports grants from Stryker Emergency Care, personal fees from Stryker Emergency Care, and personal fees from HeartSine outside the submitted work. Markus Hollmann reports non-financial support from Executive Section Editor Pharmacology with Anesthesia & Analgesia, non-financial support from Section Editor Anesthesiology with Journal of Clinical Medicine, other from CSL Behring and other from Eurocept BV outside the submitted work. René Boomars, Fabian Kooij, and Paul den Tex have nothing to disclose.

MeSH terms

LinkOut - more resources