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. 2021 Aug 1;40(8):738-740.
doi: 10.1097/INF.0000000000003129.

Risk Factors for Acquisition of Extended-spectrum Beta-lactamase and AmpC Resistant Gram-negative Bacteria in Critically Ill Infants With Congenital Heart Disease

Affiliations

Risk Factors for Acquisition of Extended-spectrum Beta-lactamase and AmpC Resistant Gram-negative Bacteria in Critically Ill Infants With Congenital Heart Disease

Andrea K Borst et al. Pediatr Infect Dis J. .

Abstract

In a cohort of 257 infants with congenital heart disease admitted to the pediatric intensive care unit, 22 infants had positive cultures for extended-spectrum beta-lactamase or AmpC Gram-negative bacteria. These infants had longer exposure to broad-spectrum antibiotics, greater support with invasive devices and longer intensive care and hospital lengths of stay.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

References

    1. World Health Organization. Antimicrobial resistance global report on surveillance.2014. World Health Organization; Available at: https://apps.who.int/iris/bitstream/handle/10665/112642/9789241564748_en... . Accessed February 7, 2019.
    1. Cheikh A, Belefquih B, Chajai Y, et al. Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) colonization as a risk factor for developing ESBL infections in pediatric cardiac surgery patients: “retrospective cohort study.” BMC Infect Dis. 2017;17:237.
    1. Meropol SB, Haupt AA, Debanne SM. Incidence and outcomes of infections caused by multidrug-resistant Enterobacteriaceae in children, 2007-2015. J Pediatric Infect Dis Soc. 2018;7:36–45.
    1. Lukac PJ, Bonomo RA, Logan LK. Extended-spectrum β-lactamase-producing Enterobacteriaceae in children: old foe, emerging threat. Clin Infect Dis. 2015;60:1389–1397.
    1. Logan LK, Renschler JP, Gandra S, et al.; Centers for Disease Control; Prevention Epicenters Program. Carbapenem-resistant Enterobacteriaceae in children, United States, 1999-2012. Emerg Infect Dis. 2015;21:2014–2021.

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