Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Apr:81:105739.
doi: 10.1016/j.ijscr.2021.105739. Epub 2021 Mar 11.

Perianal squamous cell carcinoma: A case report

Christina Eliachevsky  1 , Erin Templeton  2 , Atul K Nanda  3
Affiliations
Case Reports

Perianal squamous cell carcinoma: A case report

Christina Eliachevsky et al. Int J Surg Case Rep. 2021 Apr.

Abstract

Introduction and importance: Perianal carcinomas, though rare, are usually squamous cell carcinoma. Current literature recommends surgical excision for tumors staged T1-T2, N0 without external anal sphincter involvement, however our case demonstrated that tumors with superficial involvement of external sphincter fibers can be resected completely.

Case presentation: A 45-year-old Caucasian male presented with a perianal mass found to be squamous cell carcinoma. Initial imaging suggested the anal sphincter was spared, however intraoperatively tumor cells were found involving superficial external sphincter fibers and a portion was excised to ensure complete removal.

Clinical discussion: Perianal squamous malignancies are often misdiagnosed as more benign conditions. Treatment aims to preserve sphincter function and depends on tumor stage along with anatomical involvement.

Conclusion: Despite superficial muscle infiltration, the T2N0 perianal lesion was curable with surgical resection alone without recurrence or functional deficits reported one year later. This suggests surgical management may be possible in some cases with sphincter involvement.

Keywords: Anal margin; Case report; General surgery; Oncology; Squamous cell carcinoma.

PubMed Disclaimer

Figures

Image 1
Image 1
Fungating perianal mass.
Image 2
Image 2
Coronal plane of pelvic MRI showing the mass.
Image 3
Image 3
Transverse plane of pelvic MRI depicting the perianal mass.
Image 4
Image 4
One year after excision.
See this image and copyright information in PMC

References

    1. Surabhi V.R., Menias C.O., Amer A.M., Elshikh M., Katabathina V.S., Hara A.K. Tumors and tumorlike conditions of the anal canal and perianal region: MR imaging findings. RadioGraphics. 2016;36(5):1339–1353. doi: 10.1148/rg.2016150209. - DOI - PubMed
    1. Sahai A., Kodner I. Premalignant neoplasms and squamous cell carcinoma of the anal margin. Clin. Colon Rectal Surg. 2006;19(2):088–093. doi: 10.1055/s-2006-942349. - DOI - PMC - PubMed
    1. Gonzalez R.S. Anus & Perianal Area Carcinoma: Squamous Cell Carcinoma. https://www.pathologyoutlines.com/topic/anusscc.html [cited 2021 Feb 2]. Available from:
    1. Wietfeldt E.D., Thiele J. Malignancies of the anal margin and perianal skin. Clin. Colon Rectal Surg. 2009;22(02):127–135. doi: 10.1055/s-0029-1223845. - DOI - PMC - PubMed
    1. Agha R.A., Franchi T., Sohrabi C., Mathew G., for the SCARE Group The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines. Int. J. Surg. 2020;84:226–230. - PubMed

Publication types

LinkOut - more resources