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. 1988 Jan;79(1):73-9.
doi: 10.1007/BF00229400.

Differential phosphorylation of microtubule proteins by ATP and GTP

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Differential phosphorylation of microtubule proteins by ATP and GTP

J Diaz-Nido et al. Mol Cell Biochem. 1988 Jan.

Abstract

Purified brain microtubule protein is phosphorylated by endogenous protein kinase activities in the presence of [gamma-32P] ATP or [gamma-32P] GTP. Here we show that certain microtubule-associated proteins are phosphorylated differently by GTP or ATP as direct phosphoryl donors, suggesting the presence of distinct kinase activities, with different specificities, associated with microtubule protein.

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