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Editorial
. 2021 Apr;53(8):950-951.
doi: 10.1111/apt.16327.

Editorial: methotrexate in patients with Crohn's disease refractory to anti-TNF therapy-moving backwards yet forward?

Parul Tandon  1 , Neeraj Narula  2
Affiliations
Editorial

Editorial: methotrexate in patients with Crohn's disease refractory to anti-TNF therapy-moving backwards yet forward?

Parul Tandon et al. Aliment Pharmacol Ther. 2021 Apr.
No abstract available

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References

REFERENCES

    1. Peyrin-Biroulet L, Loftus EV Jr, Colombel J-F, Sandborn WJ. The natural history of adult Crohn's disease in population-based cohorts. Am J Gastroenterol. 2010;105:289-297.
    1. Cosnes J, Cattan S, Blain A, et al. Long-term evolution of disease behavior of Crohn's disease. Inflamm Bowel Dis. 2002;8:244-250.
    1. Papamichael K, Gils A, Rutgeerts P, et al. Role for therapeutic drug monitoring during induction therapy with TNF antagonists in IBD: evolution in the definition and management of primary nonresponse. Inflamm Bowel Dis. 2015;21:182-197.
    1. Mesonero F, Castro-Poceiro J, Benitez JM, et al. Effectiveness and safety of methotrexate monotherapy in patients with Crohn's disease refractory to anti-TNF-α: results from the ENEDIA registry. Aliment Pharmacol Ther. 2021; https://doi.org/10.1111/apt.16315.
    1. Khanna R, Ma C, Jairath V, Vande Casteele N, Zou G, Feagan BG. Endoscopic assessment of inflammatory bowel disease activity in clinical trials. Clin Gastroenterol Hepatol. 2020; in press. https://doi.org/10.1016/j.cgh.2020.12.017

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