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Review
. 2021 Apr;39(2):211-220.
doi: 10.1016/j.det.2020.12.014. Epub 2021 Feb 11.

Management of Nail Psoriasis

Affiliations
Review

Management of Nail Psoriasis

Dimitrios Rigopoulos et al. Dermatol Clin. 2021 Apr.

Abstract

Nail psoriasis is a chronic nail disorder that requires personalized treatment. General prophylactic measures are suggested for all patients. Topical treatment is considered when treating a few-nail disease, with involvement of 3 or fewer nails, without joint involvement and without (or with mild) skin psoriasis. The ideal formulation should be ointment, solution, or foam. When moderate to severe skin psoriasis or psoriatic arthritis coexists, systemic treatment is suggested. This also should be considered when more than 3 nails are affected or significant impairment of quality of life is present. Conventional systemic agents, biologics, and small molecules are highly efficacious.

Keywords: Nail bed; Nail matrix; Nail psoriasis; Nail psoriasis treatment.

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Conflict of interest statement

Conflict of interest D. Rigopoulos was a speaker and has received honoraria from Celgene, Novartis, Janssen, LEO, Lilly, UCB, and Abbvie; was a consultant and has received honoraria from Celgene, Novartis, Janssen. and Abbvie; and is/was a PI for Abbvie and Genesis Pharma. N. Rompoti was a speaker and has received honoraria from Abbvie, Genesis Pharma, Janssen, Novartis, LEO, Lilly, and UCB. S. Gregoriou was a speaker and has received honoraria from Abbvie, Janssen, and Novartis. No funding has been received for this article.

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