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. 2021 Mar 1;13(1):e2021020.
doi: 10.4084/MJHID.2021.020. eCollection 2021.

DNA Repair Genes and Chronic Myeloid Leukemia: ERCC2 (751), XRCC1 (399), XRCC4-Intron 3, XRCC4 (-1394) Gene Polymorphisms

Kursat Ozdilli  1 , Mustafa Pehlivan  2   3 , Istemi Serin  2 , Fatma Oguz Savran  4 , Ayse Gaye Tomatir  5 , Sacide Pehlivan  4
Affiliations

DNA Repair Genes and Chronic Myeloid Leukemia: ERCC2 (751), XRCC1 (399), XRCC4-Intron 3, XRCC4 (-1394) Gene Polymorphisms

Kursat Ozdilli et al. Mediterr J Hematol Infect Dis. .
No abstract available

Keywords: CML; DNA repair genes; Polymorphisms.

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Conflict of interest statement

Competing interests: The authors declare no conflict of Interest.

Figures

Figure 1
Figure 1
Kaplan-Meier Plots on Event-free Survival (EFS) According to XRCC1 genotypes.
See this image and copyright information in PMC

References

    1. Kurzrock R, Kantarjian HM, Druker BJ, Talpaz M. Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann Intern Med. 2003 May 20;138(10):819–30. doi: 10.7326/0003-4819-138-10-200305200-00010. - DOI - PubMed
    1. Das-Gupta EP, Seedhouse CH, Russell NH. DNA repair mechanisms and acute myeloblastic leu-kemia. Hematol Oncol. 2000 Sep;18(3):99–110. doi: 10.1002/1099-1069(200009)18:3<99::AID-HON662>3.0.CO;2-Z. - DOI - PubMed
    1. Taylor EM, Broughton BC, Botta E, et al. Xeroderma pigmentosum and trichothiodystrophy are as-sociated with different mutations in the XPD (ERCC2) repair/transcription gene. Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8658–63. doi: 10.1073/pnas.94.16.8658. - DOI - PMC - PubMed
    1. Artac M, Bozcuk H, Pehlivan S, et al. The value of XPD and XRCC1 genotype polymor-phisms to predict clinical outcome in metastatic colorectal carcinoma patients with irinotecan-based regimens. J Cancer Res Clin Oncol. 2010;136:803–809. doi: 10.1007/s00432-009-0720-3. - DOI - PMC - PubMed
    1. Chacko P, Rajan B, Joseph T, Mathew BS, Pillai MR. Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer. Breast Cancer Res Treat. 2005;89(1):15–21. doi: 10.1007/s10549-004-1004-x. - DOI - PubMed