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Review
. 2021 Mar 1;13(1):e2021025.
doi: 10.4084/MJHID.2021.025. eCollection 2021.

How I Treat Febrile Neutropenia

Marcio Nucci  1
Affiliations
Review

How I Treat Febrile Neutropenia

Marcio Nucci. Mediterr J Hematol Infect Dis. .

Abstract

The management of febrile neutropenia is a backbone of treating patients with hematologic malignancies and has evolved over the past decades. This article reviews my approach to the evaluation and treatment of febrile neutropenic patients. Key topics discussed include antibacterial and antifungal prophylaxis, the initial workup for fever, the choice of the empiric antibiotic regimen and its modifications, and criteria for discontinuation. For each of these questions, I review the literature and present my perspective.

Keywords: Febrile neutropenia; Fever; Management; Neutropenia.

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Conflict of interest statement

Competing interests: The authors declare no conflict of Interest.

Figures

Figure 1
Figure 1
Strategy of empiric antibiotic therapy in patients with colonization or a previous episode of infection by multi-drug-resistant Gram-negative bacteria.
See this image and copyright information in PMC

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