Claims and reasons about mild COVID-19 in children
- PMID: 33747533
- PMCID: PMC7963516
- DOI: 10.1016/j.nmni.2021.100864
Claims and reasons about mild COVID-19 in children
Abstract
The elderly form the main risk group in the coronavirus disease 2019 (COVID-19) pandemic, and age is recognized as a major risk factor for the severity of infection and mortality of COVID-19. The severity of the infection in children is milder than in adults. Although the pathophysiology of COVID-19 is not fully understood, several possible factors and mechanisms have been suggested for the lower severity of infection in children.
Keywords: Children; coronavirus disease 2019; mild infection; severe acute respiratory syndrome coronavirus 2; young people.
© 2021 The Author(s).
Similar articles
-
Silence of the Lambs: The Immunological and Molecular Mechanisms of COVID-19 in Children in Comparison with Adults.Microorganisms. 2021 Feb 7;9(2):330. doi: 10.3390/microorganisms9020330. Microorganisms. 2021. PMID: 33562210 Free PMC article. Review.
-
The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of "inflame-aging".Inflamm Res. 2020 Sep;69(9):825-839. doi: 10.1007/s00011-020-01372-8. Epub 2020 Jun 11. Inflamm Res. 2020. PMID: 32529477 Free PMC article. Review.
-
Higher severe acute respiratory syndrome coronavirus 2 infection rate in pregnant patients.Am J Obstet Gynecol. 2021 Jul;225(1):75.e1-75.e16. doi: 10.1016/j.ajog.2021.02.011. Epub 2021 Feb 16. Am J Obstet Gynecol. 2021. PMID: 33607103 Free PMC article.
-
Human and novel coronavirus infections in children: a review.Paediatr Int Child Health. 2021 Feb;41(1):36-55. doi: 10.1080/20469047.2020.1781356. Epub 2020 Jun 25. Paediatr Int Child Health. 2021. PMID: 32584199 Review.
-
Coronavirus disease 2019 (COVID-19) and pediatric gastroenterology.Gastroenterol Hepatol Bed Bench. 2020 Fall;13(4):351-354. Gastroenterol Hepatol Bed Bench. 2020. PMID: 33244377 Free PMC article. Review.
Cited by
-
Host factors and vaccine efficacy: Implications for COVID-19 vaccines.J Med Virol. 2022 Apr;94(4):1330-1335. doi: 10.1002/jmv.27485. Epub 2021 Dec 7. J Med Virol. 2022. PMID: 34845730 Free PMC article. Review.
-
COVID-19 in Pediatric Patients: An update on Features and Treatment Options.Tanaffos. 2022 Mar;21(3):283-292. Tanaffos. 2022. PMID: 37025318 Free PMC article. Review.
-
Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range.Sci Rep. 2021 Aug 5;11(1):15927. doi: 10.1038/s41598-021-95532-3. Sci Rep. 2021. PMID: 34354210 Free PMC article.
-
The attitude and knowledge of pediatricians and family physicians toward COVID-19 vaccination in children: A cross-sectional study.Hum Vaccin Immunother. 2023 Aug 1;19(2):2230104. doi: 10.1080/21645515.2023.2230104. Epub 2023 Jul 3. Hum Vaccin Immunother. 2023. PMID: 37395614 Free PMC article.
-
Efficacy of the tetravalent protein COVID-19 vaccine, SCTV01E: a phase 3 double-blind, randomized, placebo-controlled trial.Nat Commun. 2024 Jul 24;15(1):6255. doi: 10.1038/s41467-024-49832-7. Nat Commun. 2024. PMID: 39048547 Free PMC article. Clinical Trial.
References
-
- Abdoli A., Falahi S., Kenarkoohi A., Shams M., Mir H., Jahromi M.A.M. The COVID-19 pandemic, psychological stress during pregnancy, and risk of neurodevelopmental disorders in offspring: a neglected consequence. J Psychosom Obstet Gynaecol. 2020;41:247–248. - PubMed
-
- Sisk B., Cull W., Harris J.M., Rothenburger A., Olson L. National trends of cases of COVID-19 in children based on US State Health Department data. Pediatrics. 2020;146(6) - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources