Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Mar 15;9(3):e3457.
doi: 10.1097/GOX.0000000000003457. eCollection 2021 Mar.

Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap

Affiliations

Quality of Life in Palliative Post-mastectomy Reconstruction: Keystone versus Rotational Flap

Irena Sakura Rini et al. Plast Reconstr Surg Glob Open. .

Abstract

Late stage breast cancer presents with malignant wound causing skin infiltration, pain, bleeding, and malodour, which affect quality of life (QoL). Palliative mastectomy aims to eliminate wound symptoms and requires prolonged wound care to improve QoL. This study aimed to prospectively investigate QoL differences in 2 alternative reconstructive methods: keystone flap and rotational flap.

Methods: Twenty-four late stage breast cancer patients with symptoms of cancer wounds were included in this study. They were divided into 2 groups: keystone flap and rotational flap. Each patient's QoL was evaluated using EORTC QLQ-C30 and QLQ-BR23 before and 3 weeks after surgery.

Results: Global health post-surgery was significantly improved compared with pre-surgery in all patients (P < 0.001), across both the keystone (P = 0.018) and rotational groups (P = 0.007). Breast symptoms post-surgery were also improved compared with pre-surgery in all patients (P = 0.035). However, when analyzed per group, breast symptoms were only improved significantly in the keystone group (P = 0.013) but not in the rotational group (P = 0.575). When compared between 2 groups, future perspective post-surgery in the keystone group [100 (0-100)] was better than the rotational group [66.7 (0-100)], (P = 0.020).

Conclusions: Reconstructive surgery after mastectomy improves QoL in late stage breast cancer patients. The keystone flap is superior to the rotational flap in improving global health and breast symptoms.

PubMed Disclaimer

Conflict of interest statement

Disclosure: The authors have no financial interest to declare in relation to the content of this article.

Figures

Fig. 1.
Fig. 1.
Procedure for keystone flap reconstruction. A, Harvesting phase. B, Insetting phase. C, Result.
Fig. 2.
Fig. 2.
Keystone flap process. A, Breast cancer malignant wound. B, Flap design on post-mastectomy defect (note the double keystone design). C, Insetting phase. D, Direct post-reconstruction result. E, Three weeks post-reconstruction.
Fig. 3.
Fig. 3.
Rotational flap process. A, Breast cancer malignant wound. B, Flap design on post-mastectomy defect. C, Insetting phase. D, Direct post-reconstruction result. E, Three weeks post-reconstruction.

References

    1. Ferlay J, Soerjomataram I, Dikshit R, et al. . Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015; 136:E359–E386 - PubMed
    1. InfoDATIN Pusat Data dan Informasi Kementerian Kesehatan RI. Bulan Peduli Kanker Payudara. 2016; 12Available at https://pusdatin.kemkes.go.id/resources/download/pusdatin/infodatin/Info.... Accessed June 14, 2019
    1. Solikhah S, Promthet S, Rakkapao N, et al. . Validation of an Indonesian version of the Breast Cancer Awareness Scale (BCAS-I). Asian Pac J Cancer Prev. 2017; 18:515–522 - PMC - PubMed
    1. Merz T, Klein C, Uebach B, et al. . Fungating wounds – multidimensional challenge in palliative care. Breast Care (Basel). 2011; 6:21–24 - PMC - PubMed
    1. Rabin EG, Heldt E, Hirakata VN, et al. . Quality of life predictors in breast cancer women. Eur J Oncol Nurs. 2008; 12:53–57 - PubMed