Effect of dietary astaxanthin administration on the growth performance and innate immunity of juvenile crucian carp (Carassius auratus)

Abstract

The present study aims to explore the effects of oral astaxanthin administration on the growth performance and innate immunity of juvenile crucian carp (Carassius auratus). Juvenile crucian carps with a bodyweight of 40.06 ± 2.17 g were randomly assigned to four groups, i.e., one control group fed with a basic diet and three treatment groups fed with a diet that contains 200, 400 and 800 mg/kg astaxanthin. After 60 days of feeding, the groups fed with astaxanthin-containing diets had improved body weight gain rate; feed conversion ratio; intestinal digestive protease, lipase and amylase levels; serum superoxide dismutase, catalase, acid phosphatase, alkaline phosphatase and lysozyme activities; complement 3 and complement 4 levels; interleukin (IL)-10 and resistance to Aeromonas hydrophilia and reduced serum aspartate aminotransferase and alanine aminotransferase activities and tumour necrosis factor-α, IL-1β and IL-8 levels compared with those of the control group. Based on the efficiency of the oral administration of astaxanthin on the growth performance of juvenile crucian carps, the optimum dose of astaxanthin was 400 mg/kg. Results indicated that astaxanthin may be used as a dietary supplement for the crucian carp.

Keywords: Astaxanthin; Crucian carp; Growth; Immunity.

Fig. 1

Cumulative mortality (%) of crucian carp fed with astaxanthin diets, after being challenged by pathogen, Aeromonas hydrophila