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. 2021 Mar 15;7(1):e12141.
doi: 10.1002/trc2.12141. eCollection 2021.

SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)-pilot: A feasibility study

Kimberly Ann Chew  1 , Xin Xu  1   2 , Paula Siongco  3 , Steven Villaraza  3 , April Ka Sin Phua  3 , Zi Xuen Wong  3 , Chooi Yu Chung  4 , Ning Tang  5 , Effie Chew  5   6 , Christiani Jeyakumar Henry  4   7   8 , Edward Koo  9 , Christopher Chen  1   3
Affiliations

SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)-pilot: A feasibility study

Kimberly Ann Chew et al. Alzheimers Dement (N Y). .

Abstract

Introduction: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi-domain lifestyle interventions compared to Singaporean adaptations.

Methods: Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months.

Results: Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (Pupper body = .04, P lower body = .06, P core = .05). More participants in the SINGER group attained good blood pressure control at month-6 compared to FINGER (41% vs 19%; P = .06).

Discussion: This study is the first to compare the feasibility of multi-domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi-domain lifestyle interventions in preventing cognitive decline.

Keywords: cognitive impairment; dementia; feasibility; intervention; lifestyle; randomized controlled trial.

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Conflict of interest statement

None declared.

Figures

FIGURE 1
FIGURE 1
Recruitment flowchart
FIGURE 2
FIGURE 2
Timeline of study period affected by the COVID‐19 pandemic
FIGURE 3
FIGURE 3
Overall BP outcome between groups
See this image and copyright information in PMC

References

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    1. Chen C, Xu X, Chew E, Henry CJ, Koo EH. Singapore intervention study to prevent cognitive impairment and disability (singer) initiative. Alzheimers Dement. 2017;13(7).
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