Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2021 Apr 12;23(4):530-532.
doi: 10.1093/neuonc/noab026.

Fountain of chaos: cerebrospinal fluid enhancement of cancer stem cells in glioblastoma

Justin D Lathia  1   2   3   4
Affiliations
Editorial

Fountain of chaos: cerebrospinal fluid enhancement of cancer stem cells in glioblastoma

Justin D Lathia. Neuro Oncol. .
No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
SerpinA3 activation in cancer stem cells adjacent to the lateral ventricle. Schematic depicting the activation of SERPINA3 in cancer stem cells adjacent to the lateral ventricle by the cerebrospinal fluid.
See this image and copyright information in PMC

Comment on

References

    1. Lathia JD, Mack SC, Mulkearns-Hubert EE, Valentim CL, Rich JN. Cancer stem cells in glioblastoma. Genes Dev. 2015;29(12):1203–1217. - PMC - PubMed
    1. Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001;414(6859):105–111. - PubMed
    1. Lehtinen MK, Zappaterra MW, Chen X, et al. . The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron. 2011;69(5):893–905. - PMC - PubMed
    1. Ihrie RA, Alvarez-Buylla A. Lake-front property: a unique germinal niche by the lateral ventricles of the adult brain. Neuron. 2011;70(4):674–686. - PMC - PubMed
    1. Berendsen S, van Bodegraven E, Seute T, et al. . Adverse prognosis of glioblastoma contacting the subventricular zone: biological correlates. PLoS One. 2019;14(10):e0222717. - PMC - PubMed

Substances