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Comment
. 2021 Mar 21;117(4):e46-e48.
doi: 10.1093/cvr/cvab057.

Jumping on base editing to repair the diseased cardiovascular system in vivo

Monika M Gladka  1 , Andrew H Baker  2
Affiliations
Comment

Jumping on base editing to repair the diseased cardiovascular system in vivo

Monika M Gladka et al. Cardiovasc Res. .
No abstract available

Keywords: Base editing; Gene therapy; Genome editing; Hutchinson–Gilford progeria syndrome; Vascular smooth muscle.

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  • In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
    Koblan LW, Erdos MR, Wilson C, Cabral WA, Levy JM, Xiong ZM, Tavarez UL, Davison LM, Gete YG, Mao X, Newby GA, Doherty SP, Narisu N, Sheng Q, Krilow C, Lin CY, Gordon LB, Cao K, Collins FS, Brown JD, Liu DR. Koblan LW, et al. Nature. 2021 Jan;589(7843):608-614. doi: 10.1038/s41586-020-03086-7. Epub 2021 Jan 6. Nature. 2021. PMID: 33408413 Free PMC article.

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