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Review
. 2021 Apr;61(4):569-575.
doi: 10.1111/head.14102. Epub 2021 Mar 22.

Developmental innervation of cranial dura mater and migraine headache: A narrative literature review

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Review

Developmental innervation of cranial dura mater and migraine headache: A narrative literature review

Andrew Witten et al. Headache. 2021 Apr.

Abstract

Introduction: Migraine headache prevalence, etiology, and clinical presentations change from childhood to adulthood. Dural innervation plays a role in headache symptomatology, but the changes in innervation during development have not been fully explored in the literature.

Methods: A narrative literature review on developmental innervation of cranial dura mater in the context of migraine headache.

Results: Dural structures, nerve distributions, and pain attributed to migraine headache at varying stages of development are discussed herein with a focus on clinical findings and presentations.

Conclusions: There are many differences in migraine presentation throughout development. Notably, the nervus spinosus and nervus tentorii may play a role in developmental differences in migraine headache presentations between children and adults.

Keywords: adult; child; development; dura mater innervation; gender; migraine.

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