Randomized Controlled Trial
doi: 10.1136/dtb.2021.000016.
Epub 2021 Mar 22.
Tranexamic acid should be avoided for acute gastrointestinal bleeds
- PMID: 33753352
- DOI: 10.1136/dtb.2021.000016
Item in Clipboard
Randomized Controlled Trial
Tranexamic acid should be avoided for acute gastrointestinal bleeds
Drug Ther Bull.
2021 Jun.
Abstract
Overview of: The HALT-IT Trial Collaborators. Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial. Lancet 2020; 395:1927-36.
Keywords: access; drug-related side effects and adverse reactions; evaluation; healthcare quality.
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Similar articles
-
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.Lancet. 2020 Jun 20;395(10241):1927-1936. doi: 10.1016/S0140-6736(20)30848-5. Lancet. 2020. PMID: 32563378 Free PMC article. Clinical Trial.
-
In adults with severe acute GI bleeding, tranexamic acid did not reduce death due to bleeding at 5 days.Ann Intern Med. 2020 Oct 20;173(8):JC46. doi: 10.7326/ACPJ202010200-046. Ann Intern Med. 2020. PMID: 33075257
-
Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.Trials. 2019 Jul 30;20(1):467. doi: 10.1186/s13063-019-3561-7. Trials. 2019. PMID: 31362765 Free PMC article.
-
[Tranexamic acid for upper gastrointestinal bleeding].Ugeskr Laeger. 2016 Apr 11;178(15):V09150773. Ugeskr Laeger. 2016. PMID: 27094539 Review. Danish.
-
Systematic review with meta-analysis: the efficacy of tranexamic acid in upper gastrointestinal bleeding.Aliment Pharmacol Ther. 2020 Jun;51(11):1004-1013. doi: 10.1111/apt.15761. Epub 2020 May 3. Aliment Pharmacol Ther. 2020. PMID: 32363690
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
