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Multicenter Study
. 2021 Mar 1;4(3):e212640.
doi: 10.1001/jamanetworkopen.2021.2640.

Participation of Black US Residents in Clinical Trials of 24 Cardiovascular Drugs Granted FDA Approval, 2006-2020

Siliang Chen  1 , Jiarui Li  1
Affiliations
Multicenter Study

Participation of Black US Residents in Clinical Trials of 24 Cardiovascular Drugs Granted FDA Approval, 2006-2020

Siliang Chen et al. JAMA Netw Open. .

Abstract

This cross-sectional study investigates the representation status of Black US residents in clinical trials of 24 cardiovascular drugs granted US Food and Drug Administration (FDA) approval between January 1, 2006, and August 31, 2020.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Participation by Black and White US Residents in Clinical Trials Supporting Approval of Drugs to Treat Cardiovascular Disease, 2006-2020
A, The vertical dashed line at participation to prevalence ratio (PPR) of 0.8 indicates that lower values represent underrepresentation, and the dashed line of 1.2 indicates that higher values represent overrepresentation. Values from 0.8 to 1.2 indicate that the proportion of the group in clinical trials nearly equals its proportion in the disease population. B, An annual breakdown shows underrepresentation by Black US residents in cardiovascular drug trials.
See this image and copyright information in PMC

References

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