Post-operative septic arthritis after arthroscopy: modern diagnostic and therapeutic concepts
- PMID: 33755737
- PMCID: PMC8458194
- DOI: 10.1007/s00167-021-06525-8
Post-operative septic arthritis after arthroscopy: modern diagnostic and therapeutic concepts
Abstract
Purpose: Septic arthritis is a significant complication following arthroscopic surgery, with an estimated overall incidence of less than 1%. Despite the low incidence, an appropriate diagnostic and therapeutic pathway is required to avoid serious long-term consequences, eradicate the infection, and ensure good treatment outcomes. The aim of this current review article is to summarize evidence-based literature regarding diagnostic and therapeutic options of post-operative septic arthritis after arthroscopy.
Methods: Through a literature review, up-to-date treatment algorithms and therapies have been identified. Additionally, a supportive new algorithm is proposed for diagnosis and treatment of suspected septic arthritis following arthroscopic intervention.
Results: A major challenge in diagnostics is the differentiation of the post-operative status between a non-infected hyperinflammatory joint versus septic arthritis, due to clinical symptoms, (e.g., rubor, calor, or tumor) can appear identical. Therefore, joint puncture for microbiological evaluation, especially for fast leukocyte cell-count diagnostics, is advocated. A cell count of more than 20.000 leukocyte/µl with more than 70% of polymorphonuclear cells is the generally accepted threshold for septic arthritis.
Conclusion: The therapy is based on arthroscopic or open surgical debridement for synovectomy and irrigation of the joint, in combination with an adequate antibiotic therapy for 6-12 weeks. Removal of indwelling hardware, such as interference screws for ACL repair or anchors for rotator cuff repair, is recommended in chronic cases.
Level of evidence: IV.
Keywords: Ankle; Antibiotics; Arthroscopy; Complication; Elbow; Hip; Joint infection; Knee; Shoulder; Wrist.
© 2021. The Author(s).
Conflict of interest statement
The authors declare that they have no conflict of interest.
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References
-
- Ascione T, Balato G, Mariconda M, Rosa D, Rizzo M, Pagliano P. Post-arthroscopic septic arthritis of the knee. Analysis of the outcome after treatment in a case series and systematic literature review. Eur Rev Med Pharmacol Sci. 2019;23:76–85. - PubMed
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