Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul;31(7):3109-3115.
doi: 10.1007/s11695-021-05349-2. Epub 2021 Mar 23.

Evaluation of Myocardial Function Following SADI-S

Affiliations

Evaluation of Myocardial Function Following SADI-S

Adriana Ruano-Campos et al. Obes Surg. 2021 Jul.

Abstract

Purpose: The aim of this study was to compare myocardial mechanics using global longitudinal strain (GLS) before and after single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S).

Materials and methods: A total of 21 obese patients undergoing SADI-S were prospectively included. Transthoracic echocardiography was performed before and after the procedure, and left ventricle (LV) and right ventricle (RV) strain was assessed by two-dimensional speckle-tracking imaging (2DST).

Results: Mean time between pre-procedural and post-procedural echocardiograms was 9.2 ± 3.3 months. Postoperatively, %total weight loss (%TWL) was 33.0 ± 1.7 and % excess weight loss (%EWL) was 75.5 ± 3.6. Body mass index (BMI) significantly decreased after surgery (45.6 ± 1.2 vs 29.6 ± 1.0; p < 0.001). Postoperatively, LV GLS experienced a significant improvement (-19.8% ± 0.5 vs -22.2% ± 0.4; p < 0.001). Regarding other relevant functional parameters, RV free-wall strain was equally recovered (-19.1% ± 0.7 vs -21.0% ± 0.8; p 0.047).

Conclusions: This study demonstrates important and favourable changes in cardiac deformation parameters after performing SADI-S. Malabsorptive bariatric techniques such as SADI-S induce significant weight loss, leading to an improvement in subclinical myocardial function in patients with obesity.

Keywords: Global longitudinal strain; Myocardial strain; Obesity; Single anastomosis duodeno-ileal bypass; Speckle-tracking echocardiography.

PubMed Disclaimer

References

    1. Gadde KM, Martin CK, Berthoud HR, et al. Pathophysiology and management of obesity. JACC. 2018;71(1):79–84. - DOI
    1. Mottillo S, Filion KB, Genest J, et al. The metabolic syndrome and cardiovascular risk: a systematic review and meta-analysis. J Am Coll Cardiol. 2010;56:1113–32. - DOI
    1. Cañon-Montañez W, Santos A, Nunes LA, et al. Central obesity is the key component in the association of metabolic syndrome with left ventricular global longitudinal strain impairment. Rev Esp Cardiol. 2018;71(7):524–30. - DOI
    1. Collier P, Phelan D, Klein A. A test in context: myocardial strain measured by speckle-tracking echocardiography. J Am Coll Cardiol. 2017;69(8):1043–56.
    1. Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric surgery versus intensive medical therapy for diabetes: 5-year outcomes. N Engl J Med. 2017;376:641–51. - DOI

Publication types

LinkOut - more resources