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Comment
. 2021 Mar 22;31(6):R301-R303.
doi: 10.1016/j.cub.2021.01.085.

Cell biology: Centrosomes in inner space

Ulrich S Schwarz  1
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Cell biology: Centrosomes in inner space

Ulrich S Schwarz. Curr Biol. .
Free article

Abstract

Centrosome positioning is essential for many processes in animal cells, in particular during development and migration. A new study using quantitative analysis of enucleated cells plated on adhesive micropatterns reveals that microtubules position the centrosome in the geometric center of the intracellular space defined by the actin cytoskeleton.

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  • Acto-myosin network geometry defines centrosome position.
    Jimenez AJ, Schaeffer A, De Pascalis C, Letort G, Vianay B, Bornens M, Piel M, Blanchoin L, Théry M. Jimenez AJ, et al. Curr Biol. 2021 Mar 22;31(6):1206-1220.e5. doi: 10.1016/j.cub.2021.01.002. Epub 2021 Feb 19. Curr Biol. 2021. PMID: 33609453

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