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Comment
. 2021 Mar 23;14(675):eabh2798.
doi: 10.1126/scisignal.abh2798.

Teaming with NAADP

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Comment

Teaming with NAADP

Sandip Patel et al. Sci Signal. .

Abstract

NAADP is a potent Ca2+-mobilizing messenger linked to numerous Ca2+-dependent effects across the natural world. On 18 February 2021, delegates attended a virtual symposium to discuss studies of the mechanisms of action of NAADP, including the work of Gunaratne et al and Roggenkamp et al in this issue of Science Signaling.

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  • HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation.
    Roggenkamp HG, Khansahib I, Hernandez C LC, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla AV, Meier C, Fliegert R, Walseth TF, Flügel A, Diercks BP, Guse AH. Roggenkamp HG, et al. Sci Signal. 2021 Mar 23;14(675):eabd5647. doi: 10.1126/scisignal.abd5647. Sci Signal. 2021. PMID: 33758062

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