Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Apr;29 Suppl 1(Suppl 1):S5-S8.
doi: 10.1002/oby.23079.

Physiology of the Weight-Reduced State: A Report from a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

Affiliations

Physiology of the Weight-Reduced State: A Report from a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

Maren R Laughlin et al. Obesity (Silver Spring). 2021 Apr.

Abstract

Preventing regain of lost weight is the most difficult challenge in the treatment of obesity. The National Institute of Diabetes and Digestive and Kidney Diseases convened a workshop, "The Physiology of the Weight-Reduced State," on June 3 to 4, 2019, in order to explore the physiologic mechanisms of appetitive and metabolic adaptation that take place in the weight-reduced state and counter an individual's efforts to maintain reduced weight following weight loss.

PubMed Disclaimer

References

    1. LeBlanc EL, Patnode CD, Webber EM, Redmond N, Rushkin M, O’Connor EA. Behavioral and pharmacotherapy weight loss interventions to prevent obesity-related morbidity and mortality in adults: an updated systematic review for the U.S. Preventive Services Task Force. JAMA 2018;320:1172–1191. - PubMed
    1. https://www.niddk.nih.gov/news/meetings-workshops/2019/physiology-of-weight .
    1. Hall KD, Juen G. Obesity energetics: Body weight regulation and the effects of diet composition. Gastroenterology 2017;152:1718–1727. - PMC - PubMed
    1. Korner J, Aronne LJ. The emerging science of body weight regulation and its impact on obesity treatment. J Clin Invest 2003; 111:565–570. - PMC - PubMed
    1. Jakicic JM, Tate DF, Lang W, et al. Objective physical activity and weight loss in adults: the step-up randomized clinical trial. Obesity (Silver Spring) 2014; 22:2284–92. - PMC - PubMed

Publication types

MeSH terms