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Review
. 2022 May-Jun;14(3):311-316.
doi: 10.1177/19417381211003619. Epub 2021 Mar 24.

Foot and Ankle Injections in Athletes

Affiliations
Review

Foot and Ankle Injections in Athletes

Jonathan K Ochoa et al. Sports Health. 2022 May-Jun.

Abstract

Context: Injections are commonly used by health care practitioners to treat foot and ankle injuries in athletes despite ongoing questions regarding efficacy and safety.

Evidence acquisition: An extensive literature review was performed through MEDLINE, Google Scholar, and EBSCOhost from database inception to 2021. Keywords searched were injections, athletes, sports, foot and ankle, corticosteroids, platelet-rich plasma, and placental tissue. Search results included articles written in the English language and encompassed reviews, case series, empirical studies, and basic science articles.

Study design: Clinical review.

Level of evidence: Level 4.

Results: Corticosteroids, platelet-rich plasma/autologous blood, anesthetic, and placental tissue injections are commonly used in the treatment of foot and ankle injuries. Primary indications for injections in athletes include plantar fasciitis, Achilles tendinosis, isolated syndesmotic injury, and ankle impingement with varying clinical results.

Conclusions: Despite promising results from limited case series and comparative studies, the data for safety and efficacy of injections for foot and ankle injuries in athletes remain inconclusive.

Keywords: Achilles tendinitis; corticosteroid; placental tissue; plantar fasciitis; platelet-rich plasma; syndesmosis.

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Conflict of interest statement

The following authors declared potential conflicts of interest: C.E.G. is a paid consultant for Additive Orthopaedics and MedShape. R.B.A. is a paid consultant for Amniox, Artelon, Arthrex, Inc, Bioventus, Nuvasive, Wright Medical Technology, Inc, and Zimmer. A.R.H is a paid consultant for Arthrex, Inc.

References

    1. Abbasian M, Baghbani S, Barangi S, et al.. Outcomes of ultrasound-guided gastrocnemius injection with botulinum toxin for chronic plantar fasciitis. Foot Ankle Int. 2020;41:63-68. - PubMed
    1. Acosta-Olivo C, Elizondo-Rodriguez J, Lopez-Cavazos R, Vilchez-Cavazos F, Simental-Mendia M, Mendoza-Lemus O. Plantar fasciitis—a comparison of treatment with intralesional steroids versus platelet-rich plasma: a randomized, blinded study. J Am Podatri Med Assoc. 2017;107:490-496. - PubMed
    1. Ahmad J, Ahmad SH, Jones K. Treatment of plantar fasciitis with botulinum toxin: a randomized, controlled study. Foot Ank Int. 2017;38:1-7. - PubMed
    1. Akşahin E, Doğruyol D, Yüksel HY, et al.. The comparison of the effect of corticosteroids and platelet-rich plasma (PRP) for the treatment of plantar fasciitis. Arch Orthop Trauma Surg. 2012;132:781-785. - PubMed
    1. Altman RD, Latta L, Keer R, Renfree K, Hornicek F, Banovac K. Effect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in rats. J Orthop Trauma. 1995;9:392-400. - PubMed

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