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. 2021 Mar 22:54:e0728-2020.
doi: 10.1590/0037-8682-0728-2020. eCollection 2021.

Drug-Resistant Mycobacterium tuberculosis Isolates from New and Previously Treated TB Patients in China, 2017-2019

Zeng Mei Chun  1 , Jia Qing Jun  2
Affiliations

Drug-Resistant Mycobacterium tuberculosis Isolates from New and Previously Treated TB Patients in China, 2017-2019

Zeng Mei Chun et al. Rev Soc Bras Med Trop. .

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] Rev Soc Bras Med Trop. 2022 Oct 21;55:e0728B2022. doi: 10.1590/0037-8682-0728B-2020. Rev Soc Bras Med Trop. 2022. PMID: 36287510 Free PMC article.

Abstract

Introduction: Mycobacterium tuberculosis (MTB) is a causative agent of tuberculosis (TB) that causes death worldwide.

Methods: MTB was subjected to phenotypic drug-susceptibility tests (DST), and drug-resistant genes were sequenced.

Results: Previously treated patients were more likely to have positive smear results and exhibit drug resistance. New patients were more likely to be mono SM-resistant and less likely to be INH- and RIF-resistant. The most common mutations were katG (S315T), rpoB (S450L), rpsL (K43R), and embB (M306V).

Conclusions: The proportion of mono-SM-resistant TB among new patients was higher.

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Conflict of interest statement

Conflict of Interest: The authors declare that there is no conflict of interest.

Figures

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