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Book

Mononucleosis (Nursing)

Michael Mohseni  1 , Michael P. Boniface  1 , Charles Graham  2 , Chaddie Doerr  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Mononucleosis (Nursing)

Michael Mohseni et al.
Free Books & Documents

Excerpt

Mononucleosis classically presents with fever, lymphadenopathy, and tonsillar pharyngitis. The term “infectious mononucleosis” was first used in the 1920s to describe a group of students with a similar pharyngeal illness and blood laboratory findings of lymphocytosis and atypical mononuclear cells. It was only later that Epstein-Barr virus (EBV) was established as the cause of mononucleosis after an exposed healthcare worker developed a positive heterophile test.

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Conflict of interest statement

Disclosure: Michael Mohseni declares no relevant financial relationships with ineligible companies.

Disclosure: Michael Boniface declares no relevant financial relationships with ineligible companies.

Disclosure: Charles Graham declares no relevant financial relationships with ineligible companies.

Disclosure: Chaddie Doerr declares no relevant financial relationships with ineligible companies.

References

    1. Smatti MK, Al-Sadeq DW, Ali NH, Pintus G, Abou-Saleh H, Nasrallah GK. Epstein-Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update. Front Oncol. 2018;8:211. - PMC - PubMed
    1. Stemberger M, Jung C, Bogner JR. [Mononucleosis: a disease with three different etiologies]. MMW Fortschr Med. 2018 May;160(10):44-48. - PubMed
    1. Correia S, Bridges R, Wegner F, Venturini C, Palser A, Middeldorp JM, Cohen JI, Lorenzetti MA, Bassano I, White RE, Kellam P, Breuer J, Farrell PJ. Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases. J Virol. 2018 Nov 15;92(22) - PMC - PubMed
    1. Downham C, Visser E, Vickers M, Counsell C. Season of infectious mononucleosis as a risk factor for multiple sclerosis: A UK primary care case-control study. Mult Scler Relat Disord. 2017 Oct;17:103-106. - PubMed
    1. Burnard S, Lechner-Scott J, Scott RJ. EBV and MS: Major cause, minor contribution or red-herring? Mult Scler Relat Disord. 2017 Aug;16:24-30. - PubMed

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