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Review
. 2021 Mar 24;25(5):32.
doi: 10.1007/s11916-021-00944-5.

Neurological Causes of Chest Pain

Affiliations
Review

Neurological Causes of Chest Pain

Ushna Khan et al. Curr Pain Headache Rep. .

Abstract

Purpose of review: Chest pain is a very common presenting complaint among patients in the hospital, a large proportion of whom have non-cardiac chest pain (NCCP). Neurological causes of NCCP have not been previously reviewed although several causes have been identified.

Recent findings: Chest pain has been reported as a symptom of multiple neurological conditions such as migraine, epilepsy, and multiple sclerosis, with varying clinical presentations. The affected patients are often not formally diagnosed for long periods of time due to difficulties in recognizing the symptoms as part of neurological disease processes. This paper will briefly summarize well-known etiologies of chest pain and, then, review neurological causes of NCCP, providing an overview of current literature and possible pathophysiologic mechanisms.

Keywords: Epilepsy; Guillain-Barré syndrome; Migraine; Multiple sclerosis; Neurologic pain; Noncardiac chest pain.

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References

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