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. 2021 Mar 26;100(12):e25041.
doi: 10.1097/MD.0000000000025041.

Study on quantitative diagnosis model of TCM syndromes of post-stroke depression based on combination of disease and syndrome

Ji-Peng Yang  1 , Hong Zhao  1 , Yu-Zheng Du  1 , Hong-Wen Ma  2 , Qi Zhao  1 , Chen Li  1 , Yi Zhang  1 , Bo Li  1 , Hong-Xia Guo  1 , Hai-Peng Ban  1 , Hai-Ping Lin  1 , Wen-Long Gu  1 , Xiang-Gang Meng  1 , Qian Song  1 , Xiao-Xian Jin  1 , Tao Jiang  1 , Xin Du  1 , Yi-Xin Dong  3 , Hai-Lun Jiang  4 , Nan-Fang Wu  4 , Wei Liu  4 , Chang Rao  4 , Yan-Jie Tong  4 , Yu Li  1 , Jing-Ying Liu  4
Affiliations

Study on quantitative diagnosis model of TCM syndromes of post-stroke depression based on combination of disease and syndrome

Ji-Peng Yang et al. Medicine (Baltimore). .

Abstract

Background: Post-stroke depression (PSD) is one of the most common stroke complications with high morbidity. Researchers have done much clinical research on Traditional Chinese Medicine (TCM) treatment, but very little research on diagnosis. Based on the thought of combination of disease and syndrome, this study will establish a unified and objective quantitative diagnosis model of TCM syndromes of PSD, so as to improve the clinical diagnosis and treatment of PSD.

Objective: First: To establish a unified and objective quantitative diagnosis model of TCM syndromes in PSD under different disease courses, and identify the corresponding main, secondary, and concurrent symptoms, which are based on the weighting factor of each TCM symptom. Second: To find out the relationship between different stages of PSD and TCM syndromes. Clarify the main syndrome types of PSD under different stages of disease. Reveal the evolution and progression mechanism of TCM syndromes of PSD.

Methods and analysis: This is a retrospective study of PSD TCM diagnosis. Three hundred patients who were hospitalized in the First Teaching Hospital of Tianjin University of TCM with complete cases from January 2014 to January 2019 are planned to be recruited. The study will mainly collect the diagnostic information from the cases, find the related indicators of TCM and Western medicine in PSD, and clarify the relationship between different disease stages and TCM syndromes. Finally, the PSD TCM syndrome quantitative diagnosis model will be established based on the operation principle of Back Propagation (BP) artificial neural network.

Conclusion: To collect sufficient medical records and establish models to speed up the process of TCM diagnosis.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Study flow.
See this image and copyright information in PMC

References

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