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Randomized Controlled Trial
. 2021 Mar 24;11(1):6793.
doi: 10.1038/s41598-021-86258-3.

A randomized clinical trial of dentin hypersensitivity reduction over one month after a single topical application of comparable materials

Samar Hatem Abuzinadah  1 , Abdulrahman Jafar Alhaddad  2
Affiliations
Randomized Controlled Trial

A randomized clinical trial of dentin hypersensitivity reduction over one month after a single topical application of comparable materials

Samar Hatem Abuzinadah et al. Sci Rep. .

Abstract

Dentinal hypersensitivity (DH) is a condition that causes patient discomfort. To evaluate the clinical efficacy of Gluma, fluoride varnish and Tetric N-Bond self-etch system in relieving DH immediately and over 30 days following a single topical application. The present randomized clinical trial was conducted on 55 patients with an age range 20-49 years. 70 teeth in total were incorporated and randomly assigned to the three groups. Parameters examined were: Tactile, air blast, and cold stimuli. VAS was used to assess tactile stimulus whereas the Schiff Cold Scale for air blast and cold stimuli. DH was evaluated immediately, at two weeks and 1 month follow up. Gluma showed a statistically significant reduction in DH scores over other materials. It was concluded that Gluma have statistically significant results over other materials in relieving DH immediately and over 30 days following a single topical application.Trial Registration: Clinical Trials.gov Identifier: NCT04351412, King Abdulaziz University Protocol Record 129-09-19. Registered 17 April 2020 - Retrospectively registered. http://ClinicalTrials.gov/NCT04351412 .

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Patient with exposed cervical dentin surfaces and signs of erosion.
Figure 2
Figure 2
Inclusion and exclusion criteria.
Figure 3
Figure 3
CONSORT Flow Chart.
See this image and copyright information in PMC

References

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