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Editorial
. 2021 May;124(10):1613-1614.
doi: 10.1038/s41416-021-01316-x. Epub 2021 Mar 24.

No need for H2-antagonists in premedication regimens for paclitaxel infusions: less is more

Hans Gelderblom  1 , Juliette Zwaveling  2
Affiliations
Editorial

No need for H2-antagonists in premedication regimens for paclitaxel infusions: less is more

Hans Gelderblom et al. Br J Cancer. 2021 May.

Abstract

The theoretical basis for use of histamine 2 (H2)-receptor inhibitors to prevent hypersensitivity reactions for paclitaxel infusions is weak. This Editorial discusses a clinical study showing that ranitidine is not indicated any more in this setting and puts this in the context of other valuable efforts leaving non-evidence-based interventions behind us.

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Conflict of interest statement

The authors declare no competing interests.

Comment on

References

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