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Comment
. 2021 Jul;17(7):439-440.
doi: 10.1038/s41581-021-00417-3.

Targeting complement in ANCA-associated vasculitis: insights from ADVOCATE

Maria Prendecki  1   2 , Stephen P McAdoo  3   4
Affiliations
Comment

Targeting complement in ANCA-associated vasculitis: insights from ADVOCATE

Maria Prendecki et al. Nat Rev Nephrol. 2021 Jul.
No abstract available

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References

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    1. Pepper, R. J. et al. A novel glucocorticoid-free maintenance regimen for anti-neutrophil cytoplasm antibody-associated vasculitis. Rheumatology. 58, 260–268 (2019). - PubMed
    1. Jayne, D. R. W. et al. Avacopan for the treatment of ANCA-associated vasculitis. N. Engl. J. Med. 384, 599–609 (2021). - DOI
    1. Chen, M., Jayne, D. R. W. & Zhao, M. H. Complement in ANCA-associated vasculitis: mechanisms and implications for management. Nat. Rev. Nephrol. 13, 359–367 (2017). - DOI
    1. Xiao, H. et al. C5a receptor (CD88) blockade protects against MPO-ANCA GN. J. Am. Soc. Nephrol. 25, 225–231 (2014). - DOI

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