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Clinical Trial
. 2021 Mar 9:2021:5581812.
doi: 10.1155/2021/5581812. eCollection 2021.

Trainability of Health-Related and Motor Performance Fitness in Adults with Cystic Fibrosis within a 12-Month Partially Supervised Exercise Program

Matthias Welsner  1 , Wolfgang Gruber  2 , Uwe Mellies  2 , Margarete Olivier  2 , Sivagurunathan Sutharsan  1 , Christian Taube  1 , Stefanie Dillenhoefer  3 , Cordula Koerner-Rettberg  3 , Florian Stehling  2
Affiliations
Clinical Trial

Trainability of Health-Related and Motor Performance Fitness in Adults with Cystic Fibrosis within a 12-Month Partially Supervised Exercise Program

Matthias Welsner et al. Pulm Med. .

Abstract

Background: Regular physical activity plays an important role in the treatment of patients with cystic fibrosis (CF). This study is aimed at investigating the effects of a 12-month partially supervised exercise program on attributes of health-related and motor performance fitness, lung function (ppFEV1), BMI, and habitual physical activity (HPA, steps/day) in adults with CF.

Methods: Attributes of health-related and motor performance fitness were examined at the beginning (T0), after 6 (T1), and 12 months (T2) on the basis of five test items: forward bend (FB), bent knee hip extension (HE), plank leg raise (PLR), standing long jump (SLJ), and standing on one leg (OLS). Additionally, we recorded HPA by accelerometry, peak exercise performance (W peak) by an incremental cycle test, ppFEV1, and BMI. During the first six months, there was close supervision by an experienced sport therapist.

Results: 26 CF patients (8 female, mean age 26.5 ± 7.9 years; ppFEV1 53.7 ± 21.0) completed the exercise program. Significant improvements were recorded from T0 to T1 (FB: p ≤ 0.05; PLR, OLS: p ≤ 0.01) and from T0 to T2 (FB, PLR: p ≤ 0.01 and HE, OLS: p ≤ 0.05). W peak, ppFEV1, BMI, and HPA showed no significant improvement between the single test points and over the entire study period (all p > 0.05).

Conclusion: Our results show trainability of adults with CF in aspects of health-related and motor performance fitness during a partially supervised exercise program. Close supervision positively influences the results. Using a simple test setup seems to be a promising tool for evaluating the effects of exercise programs in CF and could serve as an additional outcome parameter in future clinical trials. Trial registration: ClinicalTrials.gov (retrospectively registered May 8, 2018).

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Timeline CFmobil.
Figure 2
Figure 2
Absolute change (in %) of the individual test items. FB: forward bend; HE: bent knee hip extension; PLR: plank leg raise; SLJ: standing long jump; OLS: standing on one leg; Wpeak: peak work load; ppFEV1: percent predicted forced expiratory volume in 1 second; BMI: body mass index; HPA: habitual physical activity.
See this image and copyright information in PMC

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