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. 2021 Oct;34(5):1501-1509.
doi: 10.1007/s40620-020-00953-4. Epub 2021 Mar 25.

Acute renal infarction: long-term renal outcome and prognostic factors

Arnaud Delezire #  1 , Marianne Terrasse #  2 , Julien Bouet  3 , Maxence Laot  4 , Vanessa Brun  4 , Emmanuel Oger  5   6 , Cécile Vigneau  2   7
Affiliations

Acute renal infarction: long-term renal outcome and prognostic factors

Arnaud Delezire et al. J Nephrol. 2021 Oct.

Abstract

Introduction: Acute renal infarction is a rare occurence, whose prognosis and long-term outcomes remain poorly studied. This study evaluated whether clinical and radiological features at diagnosis can be associated with the long-term outcomes (blood pressure, kidney function and mortality).

Methods: We retrospectively analyzed the demographic, clinical, biological and radiological data of patients with acute renal infarction hospitalized at Rennes University Hospital between 1997 and 2017 (n = 94).

Results: Patients were followed-up for a median of 60 months. At time of diagnosis of acute renal infarction median age was 53 years, 45% of the patients had acute hypertension, and 31% had Acute Kidney Injury (AKI) requiring dialysis in seven patients. The median Lactate DeHydrogenase (LDH) level was 977 IU/mL. The median extent of kidney damage was 14%, with left renal involvement in 51% of patients. At 60 months of follow-up, 66% of patients had developed Chronic Kidney Disease (CKD) stage 3 or higher, and 55% had hypertension since diagnosis. Age, acute development of hypertension and AKI at diagnosis were associated with long-term CKD (stage 3 or higher) in multivariate analyses, but the extent of kidney damage was not. During the follow-up, 21% of patients died, and only age resulted as a predisposing factor. No tested factor was correlated with long-term hypertension.

Discussion: Age, acute development of hypertension, and AKI were correlated with long term CKD, whereas no factor was correlated with long-term hypertension after acute renal infarction.

Keywords: Acute kidney injury; Chronic kidney disease; Hypertension; Renal infarction.

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References

    1. Lessman RK (1978) Renal artery embolism: clinical features and long-term follow-up of 17 cases. Ann Intern Med 89(4):477 - DOI
    1. Antopolsky M, Simanovsky N, Stalnikowicz R, Salameh S, Hiller N (2012) Renal infarction in the ED: 10-year experience and review of the literature. Am J Emerg Med 30(7):1055–1060 - DOI
    1. Nagasawa T, Matsuda K, Takeuchi Y, Fukami H, Sato H, Saito A et al (2016) A case series of acute renal infarction at a single center in Japan. Clin Exp Nephrol 20(3):411–415 - DOI
    1. Domanovits H, Paulis M, Nikfardjam M, Meron G, Kürkciyan I, Bankier AA et al (1999) Acute renal infarction: clinical characteristics of 17 patients. Medicine 78(6):386–394 - DOI
    1. Huang C-C, Lo H-C, Huang H-H, Kao W-F, Yen DH-T, Wang L-M et al (2007) ED presentations of acute renal infarction. Am J Emerg Med 25(2):164–169 - DOI

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