Amyloid-Associated Depression-or Not?

Affiliations

¹ Alzheimer's Disease Research Unit, Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut. Electronic address: christopher.vandyck@yale.edu.
² Alzheimer's Disease Research Unit, Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.

Comment

Christopher H van Dyck et al. Biol Psychiatry. 2021.

. 2021 Apr 15;89(8):737-738.

doi: 10.1016/j.biopsych.2021.02.008.

¹ Alzheimer's Disease Research Unit, Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut. Electronic address: christopher.vandyck@yale.edu.
² Alzheimer's Disease Research Unit, Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut.

No abstract available

Comment on

Late-Life Depression Is Associated With Reduced Cortical Amyloid Burden: Findings From the Alzheimer's Disease Neuroimaging Initiative Depression Project.
Mackin RS, Insel PS, Landau S, Bickford D, Morin R, Rhodes E, Tosun D, Rosen HJ, Butters M, Aisen P, Raman R, Saykin A, Toga A, Jack C Jr, Koeppe R, Weiner MW, Nelson C; Alzheimer’s Disease Neuroimaging Initiative and the ADNI Depression Project. Mackin RS, et al. Biol Psychiatry. 2021 Apr 15;89(8):757-765. doi: 10.1016/j.biopsych.2020.06.017. Epub 2020 Jul 2. Biol Psychiatry. 2021. PMID: 32980132 Free PMC article.

1. Mackin RS, Insel PS, Landau S, Bickford D, Morin R, Rhodes E, et al. (2021): Late-life depression is associated with reduced cortical amyloid burden: Findings from the Alzheimer’s Disease Neuroimaging Initiative Depression Project. Biol Psychiatry 89:757–765. - PMC - PubMed
1. Rapp MA, Schnaider-Beeri M, Grossman HT, Sano M, Perl DP, Purohit DP, et al. (2006): Increased hippocampal plaques and tangles in patients with Alzheimer disease with a lifetime history of major depression. Arch Gen Psychiatry 63:161–167. - PubMed
1. Kumar A, Kepe V, Barrio JR, Siddarth P, Manoukian V, Elderkin-Thompson V, et al. (2011): Protein binding in patients with late-life depression. Arch Gen Psychiatry 68:1143–1150. - PMC - PubMed
1. Wu KY, Hsiao IT, Chen CS, Chen CH, Hsieh CJ, Wai YY, et al. (2014): Increased brain amyloid deposition in patients with a lifetime history of major depression: Evidenced on 18F-florbetapir (AV-45/Amyvid) positron emission tomography. Eur J Nucl Med Mol Imaging 41:714–722. - PubMed
1. Krell-Roesch J, Lowe VJ, Neureiter J, Pink A, Roberts RO, Mielke MM, et al. (2018): Depressive and anxiety symptoms and cortical amyloid deposition among cognitively normal elderly persons: The Mayo Clinic Study of Aging. Int Psychogeriatr 30:245–251. - PMC - PubMed