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Comment
. 2021 Mar 25;57(3):2100274.
doi: 10.1183/13993003.00274-2021. Print 2021 Mar.

P aO2 / F IO2 ratio: the mismeasure of oxygenation in COVID-19

Affiliations
Comment

P aO2 / F IO2 ratio: the mismeasure of oxygenation in COVID-19

Martin J Tobin et al. Eur Respir J. .

Abstract

PaO2 is the most precise measurement of patient oxygenation in COVID-19, but its accuracy is corrupted when communicated as PaO2/FIO2 ratio https://bit.ly/3tNipTJ

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Conflict of interest statement

Conflict of interest: A. Jubran reports a grant from National Institute of Nursing Research (R01-NR016055) during the conduct of the study. Conflict of interest: F. Laghi reports a grant from Veterans Administration Research (1 I01 RX002803-01A1) during the conduct of the study. Conflict of interest: M.J. Tobin receives royalties for two books on critical care published by McGraw-Hill, Inc., New York.

Comment on

References

    1. Tobin MJ, Jubran A, Laghi F. Noninvasive strategies in COVID-19: epistemology, randomised trials, guidelines, physiology. Eur Respir J 2021; 57: 2004247. doi:10.1183/13993003.04247-2020. - DOI - PMC - PubMed
    1. Hakim R, Watanabe-Tejada L, Sukhal S, et al. . Acute respiratory failure in randomized trials of noninvasive respiratory support: a systematic review of definitions, patient characteristics, and criteria for intubation. J Crit Care 2020; 57: 141–147. doi:10.1016/j.jcrc.2020.02.018 - DOI - PubMed
    1. Tobin MJ, Jubran A, Laghi F. Hypoxaemia does not necessitate tracheal intubation in COVID-19 patients. Comment on Br J Anaesth 2021; 126: 44-7. Br J Anaest 2021; 126: e75-e76. doi:10.1016/j.bja.2020.11.007 - DOI - PMC - PubMed
    1. Bazuaye EA, Stone TN, Corris PA, et al. . Variability of inspired oxygen concentration with nasal cannulas. Thorax 1992; 47: 609–611. doi:10.1136/thx.47.8.609 - DOI - PMC - PubMed
    1. Murray JF, Matthay MA, Luce JM, et al. . An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988; 138: 720–723. doi:10.1164/ajrccm/138.3.720 - DOI - PubMed

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