Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jul-Dec;14(2):158-166.
doi: 10.4103/ajts.AJTS_72_18. Epub 2020 Dec 19.

Platelets transfusion in Greece: Where, when, why? A national survey

Affiliations

Platelets transfusion in Greece: Where, when, why? A national survey

Serena Valsami et al. Asian J Transfus Sci. 2020 Jul-Dec.

Abstract

Background: Platelet transfusion is among the most useful therapeutic tools in modern clinical settings which mean that ensuring an adequate supply is of paramount importance.

Aim: The aim of our study was to record the use and wastage of platelet concentrates (PCs) in Greece, so as to come up with evidence-based interventions.

Methods: The study was conducted during May and June 2015. We evaluated the use of random-donor platelets (RDPs) and single-donor apheresis platelets (SDPs). We analyzed such parameters as hospital department and diagnosis, indication for transfusion, PCs' age at the time of transfusion, and wastage rate.

Results: We used data from 21 hospitals across the country. A total of 12,061 RDPs and 1189 SDPs were transfused, with an average of 4.84 (±2.72) and 1.12 (±2.73) units per episode, respectively. Most patients had been admitted to the internal medicine and hematology departments. The transfusions were mostly given prophylactically, usually in cases of acute leukemia, and mostly on the day before expiration. Wastage rate was 16.75% for RPDs and 2.70% for SDPs, primarily because of the expiration of the use-by date.

Conclusions: This is the first national survey regarding platelet transfusion in Greece. Since most patients were admitted in internal medicine and hematology departments, we recommend that the staff of the abovementioned departments should undergo training on contemporary transfusion guidelines. Platelet discard rate could further be lowered through the centralization of inventory management along with the extension of the lifetime of PCs by means of emerging technologies.

Keywords: National; platelet; platelet products; platelets transfusion; survey.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Percentages of RDPs and RDPs transfused according to transfusion day. RDPs = Random-donors platelets, SDPs = Single-donor platelets

Similar articles

Cited by

  • Platelet transfusions in adult thrombocytopenic ICU patients: Protocol for a sub-study of the PLOT-ICU cohort.
    Anthon CT, Pène F, Perner A, Azoulay E, Puxty K, Van De Louw A, Chawla S, Castro P, Povoa P, Coelho L, Metaxa V, Kochanek M, Liebregts T, Kander T, Sivula M, Møller MH, Russell L. Anthon CT, et al. Acta Anaesthesiol Scand. 2024 Mar;68(3):434-440. doi: 10.1111/aas.14365. Epub 2023 Dec 19. Acta Anaesthesiol Scand. 2024. PMID: 38115558 Free PMC article.
  • Current Practice in FFP Preparation and Use in Greece: A National Survey.
    Argyrou A, Valsami S, Pouliakis A, Gavalaki M, Aggelidis A, Voulgaridou V, Pliatsika V, Adraktas T, Papachronis A, Alepi C, Giannopoulou V, Siourounis P, Tsagia S, Martinis G, Kontekaki E, Zervou E, Koliofotis S, Kyriakou E, Mougiou A, Dimitra L, Chairopoulou A, Tsakania A, Baka M, Apostolidou I, Moschandreou D, Livada A, Politou M, Roussinou F, Pappa C, Koika V, Vgontza N, Gafou A, Dendrinou I, Sakellaridi F, Labrianou L, Alexandropoulou Z, Sochali V, Malekas K, Skordilaki A, Kakava G, Lebesopoulos K, Stamoulis K, Grouzi E. Argyrou A, et al. Turk J Haematol. 2021 Feb 25;38(1):22-32. doi: 10.4274/tjh.galenos.2020.2020.0241. Epub 2020 Nov 22. Turk J Haematol. 2021. PMID: 33233876 Free PMC article.

References

    1. Verma A, Agarwal P. Platelet utilization in the developing world: Strategies to optimize platelet transfusion practices. Transfus Apher Sci. 2009;41:145–9. - PubMed
    1. Estcourt LJ, Birchall J, Lowe D, Grant-Casey J, Rowley M, Murphy MF. Platelet transfusions in haematology patients: Are we using them appropriately? Vox Sang. 2012;103:284–93. - PubMed
    1. Pérez Vaquero MÁ, Gorria C, Lezaun M, López FJ, Monge J, Eguizabal C, et al. Optimization of the management of platelet concentrate stocks in the Basque country using mathematical simulation. Vox Sang. 2016;110:369–75. - PubMed
    1. Estcourt LJ, Birchall J, Allard S, Bassey SJ, Hersey P, Kerr JP, et al. Guidelines for the use of platelet transfusions. Br J Haematol. 2017;176:365–94. - PubMed
    1. Australian and New Zealand Society of Blood Transfusion. Sydney. 2nd ed. Australia: Australian and New Zealand Society of Blood Transfusion Ltd; 2011. [Last accessed on 2018 Jun 30]. Guidelines for the Administration of Blood Products; pp. 1–56. Available from: https://www.anzsbt.org.au/data/documents/guidlines/ANZSBT_Guidelines_Adm... .