Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Oct-Dec;11(4):231-235.
doi: 10.4103/jmh.JMH_110_20. Epub 2021 Jan 21.

Predictors of Unsatisfactory Conventional Pap Smears

Affiliations

Predictors of Unsatisfactory Conventional Pap Smears

Reetika Sharma et al. J Midlife Health. 2020 Oct-Dec.

Abstract

Objective: The objective of this study is to determine the clinical predictors of unsatisfactory Pap smears.

Methodology: This was a case-control study done in a tertiary care institute. All unsatisfactory conventional pap (CP) smears between January 2015 and June 2017 were retrieved, and the slides were viewed. Clinical details were recorded from request forms and case files. Simple and multiple logistic regression analyses were used to identify the predictors of unsatisfactory CP smears.

Results: In this study, we have included 314 unsatisfactory Pap smears and 541 controls with satisfactory Pap smears. Clinical parameters such as older age and cervical erosion proved to be important predictors of unsatisfactory pap smears. The most common reason for unsatisfactory pap smears was due to a paucity of epithelial elements (66.6%), followed by obscuration of smear details by blood/inflammatory cells/mucus (9.9%) and air drying artifacts (4.4%). There were multiple reasons in 19.1% of cases with unsatisfactory pap smears.

Conclusion: Our study shows that older age groups and cervical erosion are predictors of unsatisfactory pap smears. Incidence of unsatisfactory pap smears can be reduced by education and retraining of health-care workers and doctors.

Keywords: Case-control studies; mass screening/methods; papanicolaou test; uterine cervical neoplasms/prevention and control.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

References

    1. Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, et al. Estimates of incidence and mortality of cervical cancer in 2018: A worldwide analysis. Lancet Glob Health. 2020;8:e191–203. - PMC - PubMed
    1. Owens CL, Buist DS, Peterson D, Kamineni A, Weinmann S, Ross T, et al. Follow-up and clinical significance of unsatisfactory liquid-based pap tests. Cancer Cytopathol. 2015;123:59–65. - PMC - PubMed
    1. Paulin H, Geldenhuys L, Naugler C. Predictors of an unsatisfactory conventional cervical cytology smear. J Obstet Gynaecol Can. 2011;33:725–8. - PubMed
    1. Quiroga-Garza G, Satrum LS, Trujillo CJ, Mody DR, Ge Y. Common causes for unsatisfactory Pap tests in a high-risk population: Insights into a yet unresolved problem in gynecologic cytology. J Am Soc Cytopathol. 2014;3:256–60. - PubMed
    1. Mood NI, Jazayerisn SN, Eftekhar Z. Clinicopathologic correlation of the unsatisfactory papanicolaou smear. Acta Medica Iranica. 2004;42:371–4.