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. 2021;6(1):1-4.
doi: 10.1080/23808993.2021.1854611.

Proteome-based pathology: the next frontier in precision medicine

Michael H Roehrl  1   2 , Victor B Roehrl  3 , Julia Y Wang  3
Affiliations

Proteome-based pathology: the next frontier in precision medicine

Michael H Roehrl et al. Expert Rev Precis Med Drug Dev. 2021.
No abstract available

Keywords: autoimmunity; cancer; clinical trial; diagnostics; drug development; mass spectrometry; pathology; precision medicine; proteomics.

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Conflict of interest statement

Declaration of Interest VBR declares no conflicts of interest related to this study. JYW is founder and equity holder of Curandis. MHR is member of the Scientific Advisory Boards of Proscia, Trans-Hit, and Universal DX. None of these companies had any influence on support, design, execution, data analysis, or any other aspect of this paper. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

Figures

Figure 1
Figure 1
(A) The identical twin thought experiment to illustrate why proteomics “sees” more than nucleic acid-only approaches. (B) An integrated multi-omic diagnostic approach to human disease requires proteomics. (C) Example of Proteome-Based Diagnostics and proteomic classification of 3 types of colon cancer metastases (Meta 1–3) that are characterized by unique sets of upregulated proteins.
See this image and copyright information in PMC

References

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