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Case Reports
. 2021 Jan 8;9(3):1228-1234.
doi: 10.1002/ccr3.3738. eCollection 2021 Mar.

How I treat obesity and obesity related surgery in patients with chronic myeloid leukemia: An outcome of an ELN project

Affiliations
Case Reports

How I treat obesity and obesity related surgery in patients with chronic myeloid leukemia: An outcome of an ELN project

Mohamed A Yassin et al. Clin Case Rep. .

Abstract

Obesity may affect treatment outcome in CML patients, therefore the treatment of this cohort of patients need careful monitoring, TKIs dose adjustment may be required for certain patients. Further studies are needed to determine the proper TKIs doses.

Keywords: TKIs level; chronic myeloid leukemia; obesity; surgery; tyrosine kinase inhibitors.

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Conflict of interest statement

Authors declare no competing interests.

Figures

FIGURE 1
FIGURE 1
Imatinib as upfront for Morbid Obese patient with CML
FIGURE 2
FIGURE 2
Imatinib post sleeve Gastrectomy
FIGURE 3
FIGURE 3
TKIs post gastric band

References

    1. Bray GA. The Battle of the Bulge: A History of Obesity Research. Pittsburgh, Penn: Dorrance Pub; 2007. Print.
    1. NHLBI Obesity Education Initiative Expert Panel on the Identification, Evaluation, and Treatment of Obesity in Adults (US) . Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults. The Evidence Report. Bethesda (MD): National Heart, Lung, and Blood Institute; 1998. Available from: https://www.ncbi.nlm.nih.gov/books/NBK2003/
    1. World Health Organization . Obesity: preventing and managing the global epidemic: report of a WHO consultation. World Health Organ Tech Rep Ser. 2000;894:i‐xii, 1‐253. - PubMed
    1. Turkina A, Wang J, Mathews V, et al. TARGET: a survey of real‐world management of chronic myeloid leukaemia across 33 countries. Br J Haematol. 2020;190(6):869‐876. - PubMed
    1. Preston D, Kusumi S, Tomonaga M, et al. Cancer incidence in atomic bomb survivors. Part III: Leukemia, lymphoma and multiple myeloma, 1950‐1987. Radiat Res. 1994;137(2):68‐97. - PubMed

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