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. 2021 Jan 16;9(3):1797-1798.
doi: 10.1002/ccr3.3768. eCollection 2021 Mar.

New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate

Najla Daadaa  1 , Soumaya Youssef  1 , Abdeddayem Haggui  2 , Sarra Harbaoui  1 , Kahena Jaber  1 , Nejib Doss  1 , Mohamed Raouf Dhaoui  1
Affiliations

New onset of sinoatrial block in a young patient treated with systemic meglumine antimoniate

Najla Daadaa et al. Clin Case Rep. .

Abstract

The sinoatrial block is a new side effect of meglumine antimoniate. Prompt interruption of the drug results in the normalization of electrographic changes and prevents sudden cardiac arrest.

Keywords: cardiotoxicity; cutaneous leishmaniasis; meglumine antimoniate.

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Conflict of interest statement

No conflict of interest.

Figures

FIGURE 1
FIGURE 1
ECG before meglumine antimoniate: Positive T waves in V4‐V5‐V6, QTc = 410 ms, FC = 78 bpm
FIGURE 2
FIGURE 2
ECG after 10 days of meglumine antimoniate: Flattened T waves in V3‐V4‐V5‐V6, sinoauricular block type 2, QTc = 474 ms, FC = 50 bpm
FIGURE 3
FIGURE 3
ECG 4 days after interrupting meglumine antimoniate: Positive T waves in V4‐V5‐V6, QTc = 428 ms, FC = 57 bpm
See this image and copyright information in PMC

References

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