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. 2021 Jul 10;39(20):2227-2231.
doi: 10.1200/JCO.20.03681. Epub 2021 Mar 26.

Rethinking Success in Pediatric Oncology: Beyond 5-Year Survival

AnnaLynn M Williams  1 , Qi Liu  2 , Nickhill Bhakta  1   3 , Kevin R Krull  1   4 , Melissa M Hudson  1   5 , Leslie L Robison  1 , Yutaka Yasui  1
Affiliations

Rethinking Success in Pediatric Oncology: Beyond 5-Year Survival

AnnaLynn M Williams et al. J Clin Oncol. .

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] J Clin Oncol. 2022 Jul 10;40(20):2283. doi: 10.1200/JCO.22.01230. J Clin Oncol. 2022. PMID: 35793562 Free PMC article. No abstract available.
No abstract available

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Conflict of interest statement

Kevin R. KrullPatents, Royalties, Other Intellectual Property: Royalties from Wolters Kluwer Melissa M. HudsonConsulting or Advisory Role: Oncology Research Information Exchange Network, Princess Máxima CenterNo other potential conflicts of interest were reported.

Figures

FIG 1.
FIG 1.
(A) Estimated numbers and proportions of excess deaths among childhood and adolescent cancer cases diagnosed at 0-19 years of age in the United States between 1975 and 2016, according to years from diagnosis by diagnosis, sex, and race (≤ 5.0 years after diagnosis [majority of excess deaths would be related to progressive disease, infection, or acute toxicity]; 5.0-9.9 years [excess deaths would reflect a mixture of recurrence or progressive disease plus deaths associated with treatment exposures]; ≥ 10.0 years post diagnosis [majority of excess deaths would be related to treatment exposures, with few from recurrence or progressive disease]); (B) estimated numbers of excess deaths among all childhood and adolescent cancer diagnosed at 0-19 years of age in the United States between 1975 and 2016, according to calendar year of death and years from diagnosis; (C) estimated numbers of excess deaths; and (D) absolute excess deaths per 1,000 patients or survivors at risk among childhood and adolescent patients with ALL, CNS malignancy, and HL, diagnosed at 0-19 years of age in the United States between 1975 and 2016, according to calendar year of death and years from diagnosis. ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; ES, Ewing sarcoma; GCT, germ cell tumor; HL, Hodgkin lymphoma; Liver, liver carcinomas; NBL, neuroblastoma; NHL, non-Hodgkin lymphoma; OS, osteosarcoma; RB, retinoblastoma; Renal, renal carcinomas; Rhabdo, rhabdomyosarcoma; STS, soft-tissue sarcoma.
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