doi: 10.1002/ajmg.1320290312.
Cytogenetic analysis of 688 couples experiencing multiple spontaneous abortions
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- PMID: 3376998
- DOI: 10.1002/ajmg.1320290312
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Cytogenetic analysis of 688 couples experiencing multiple spontaneous abortions
Am J Med Genet.
1988 Mar.
Abstract
We report on cytogenetic analysis of 688 couples experiencing two or more first- and/or second-trimester abortions (less than 20 weeks). The overall abnormality rate was 6.83% (47 couples). However, exclusion of those anomalies not generally accepted as being causal in spontaneous abortion leaves an abnormality rate of only 2.33% (16 couples). We discuss the significance of balanced translocations, inversions, sex chromosome aneuploidies, and mosaicisms thereof in the causation of multiple abortions.
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