Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 May:124:108286.
doi: 10.1016/j.jsat.2021.108286. Epub 2021 Jan 9.

Sexual-risk reduction following the referral of syringe exchange registrants to methadone maintenance: Impact of gender and drug use

Affiliations

Sexual-risk reduction following the referral of syringe exchange registrants to methadone maintenance: Impact of gender and drug use

Michael Kidorf et al. J Subst Abuse Treat. 2021 May.

Abstract

This study evaluates the impact of enrolling syringe exchange registrants in methadone maintenance on change in sexual-risk behaviors. Baltimore Needle Exchange Program (BNEP) registrants (n = 210) participated in a parent study evaluating strategies for initiating methadone maintenance treatment and the study followed them for six months. Study staff administered the Risk Assessment Battery (RAB; Metzger, 1993) monthly throughout treatment. Staff conducted urinalysis testing weekly. Results showed that treatment enrollment reduced sexual-risk behaviors at month 1, though a longer treatment duration provided no further reductions in risky behaviors. Women reported higher levels of sexual risk throughout the observation period, and the use of cocaine diminished risk-reduction benefits. These findings demonstrate that participation in methadone maintenance reduces sexual-risk behaviors in syringe exchange registrants. Efforts to help more patients reduce cocaine use, and to help women address gender-specific psychosocial vulnerabilities, may further reduce risky behaviors during the treatment episode.

Keywords: Methadone maintenance; Sexual risk reduction; Syringe exchange.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest

No conflict declared.

Figures

Fig. 1.
Fig. 1.
Sexual-risk scores over time.
Fig. 2.
Fig. 2.
Impact of gender on sexual-risk scores over time.
Fig. 3.
Fig. 3.
Impact of cocaine use on sexual-risk scores over time.

Similar articles

Cited by

References

    1. Amato L, Minozzi S, Davoli M, & Vecchi S (2011). Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence. Cochrane Database Systematic Review, 5(10), CD0044147. Doi: 10.1002/14651858.CD004147.pub4 - DOI - PubMed
    1. Aspinall EJ, Nambiar D, Goldberg DJ, Hickman M, Weir A, Van Velzen E, Palmateer N, Doyle JS, Hellard ME, & Hutchinson SJ (2014). Are needle and syringe programmes associated with a reduction in HIV transmission among people who inject drugs: A systematic review and meta-analysis. International Journal of Epidemiology, 43, 235–248. Doi:10.1093/ije/dyt243 - DOI - PubMed
    1. Avants SK, Margolin A, Usubiaga MH, & Doebrick C (2004). Targeting HIV-related outcomes with intravenous drug users maintained on methadone: A randomized clinical trial of a harm reduction group therapy. Journal of Substance Abuse Treatment, 26, 67–78. Doi: 10/1016/SO740–5472(03)00159–4 - PubMed
    1. Brookmeyer KA, Haderxhanaj LT, Hogben M, & Leichliter J (2019). Sexual risk behaviors and STDs among persons who inject drugs: A national study. Prevention Medicine, 126, 1–18. Doi: 10.1016/j.ypmed.2019.105799 - DOI - PMC - PubMed
    1. Brooner RK, King VL, Kidorf M, Schmidt CW, & Bigelow GE (1997). Psychiatric and substance use comorbidity among treatment-seeking opioid abusers. Archives of General Psychiatry, 54, 71–80. DOI: 10.1001/archpsyc.1997.01830130077015 - DOI - PubMed

Publication types