Review
doi: 10.1016/j.micinf.2021.104815.
Epub 2021 Mar 26.
Cause or effect? The spatial organization of pathogens and the gut microbiota in disease
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- PMID: 33775859
- DOI: 10.1016/j.micinf.2021.104815
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Review
Cause or effect? The spatial organization of pathogens and the gut microbiota in disease
Microbes Infect.
2021 Jul-Aug.
Free article
Abstract
The human gut hosts a dense and diverse microbial community, spatially organized in multiple scales of structure. Here, we review how microbial organization differs between health and disease. We describe how changes in spatial organization may induce alterations in gut homeostasis, concluding with a future outlook to reveal causality.
Keywords: Community dynamics; Intestinal mucus; Intestinal pathogenesis; Microbial biogeography; Microbiome.
Copyright © 2021 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.
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